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2012

Arora D, Köthe S, van den Eijnden M, van Huijsduijnen R H, Heidel F, Fischer T, Scholl S, Toelle B, Böhmer S-A, Lennartsson J, Isken F, Müller-Tidow C, Böhmer FD. Expression of protein-tyrosine phosphatases in Acute Myeloid Leukemia cells: FLT3 ITD sustains high levels of DUSP6 expression. Cell Commun Signal. 2012 Jul 11;10(1):19.

Berod L, Puttur F, Huehn J, Sparwasser T. Tregs in infection and vaccinology: heroes or traitors? Microb Biotechnol. 2012 Mar;5(2):260-9.

Brandt S, Mertens PR. Epidermal growth factor receptor mediates injury in rapidly progressive glomerular disease. Int Urol Nephrol. 2012 Jun;44(3):971-5.

Brandt S, Raffetseder U, Djudjaj S, Schreiter A, Kadereit B, Michele M, Pabst M, Zhu C, Mertens PR. Cold shock Y-box protein-1 participates in signaling circuits with auto-regulatory activities. Eur J Cell Biol. 2012 Jun-Jul;91(6-7):464-71.

Buss H, K Handschick, N Jurrmann, P Pekkonen, K Beuerlein, H Müller, R Wait, J Saklatvala, P-M Ojala, M-L Schmitz, M Naumann, M Kracht. Cyclin-Dependent Kinase 6 Phosphorylates NF-κB P65 at Serine 536 and Contributes to the Regulation of Inflammatory Gene Expression. PLOS ONE. 2012. 7: e51847.

Czöndör, K, Mondin, M, Garcia, M, Heine, M, Frischknecht, R, Choquet, D, Sibarita, JB, Thoumine OR. Unified quantitative model of AMPA receptor trafficking at synapses. Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):3522-7.

Djudjaj S, Chatziantoniou C, Raffetseder U, Guerrot D, Dussaule JC, Boor P, Kerroch M, Hanssen L, Brandt S, Dittrich A, Ostendorf T, Floege J, Zhu C, Lindenmeyer M, Cohen CD, Mertens PR. Notch-3 receptor activation drives inflammation and fibrosis following tubulointerstitial kidney injury. J Pathol. 2012 Nov;228(3):286-99.

Händel U, Brunn A, Drögemüller K, Müller W, Deckert M, Schlüter D. Neuronal gp130 expression is crucial to prevent neuronal loss, hyperinflammation, and lethal course of murine Toxoplasma encephalitis. Am J Pathol. 2012 Jul;181(1):163-73.

Hansen W, Hutzler M, Abel S, Alter C, Stockmann C, Kliche S, Albert J, Sparwasser T, Sakaguchi S, Westendorf AM, Schadendorf D, Buer J, Helfrich I. Deletion of Neuropilin-1 expression on CD4+Foxp3+ regulatory T cells impairs tumor growth in mouse melanoma. J Exp Med. 2012 October 22; 209(11): 2001-2016.

Hasenberg M, Stegemann-Koniszewski S, Gunzer M. Cellular immune reactions in the lung. Immunological Reviews. IMR-2012-054.R1

Heidel FH, Bullinger L, Feng Z, Wang Z, Neff TA, Stein L, Kalaitzidis D, Lane SW, Armstrong SA. Genetic and pharmacologic inhibition of b-Catenin targets Imatinib resistant leukemia stem cells in CML. Cell Stem Cell. 2012 Apr 6;10(4):412-24.

Heine, M. Surface traffic in synaptic membranes. Adv Exp Med Biol. 2012;970:197-219.

Jensen F, Wallukat G, Herse F, Budner O, El-Mousleh T, Costa SD, Dechend R, Zenclussen AC. CD19+CD5+ cells as indicators of pre-eclampsia. Hypertension 2012 Apr;59(4):861-868.

Karpova A, Bär J, Kreutz MR. Long-distance signaling from synapse to nucleus via protein messengers. Adv Exp Med Biol. 2012;970:355-76.

Kliche S*, Worbs T, Wang X, Degen J, Patzak I, Meineke B, Togni M, Moser M, Reinhold A, Kiefer F, Freund C, Förster R, Schraven B. CCR7-mediated LFA-1 functions in T cells are regulated by two independent ADAP/SKAP55-modules. Blood. 2012;119(3):777-785. * corresponding author

Kliese, N, Gobrecht, P, Pachow, D, Andrae, N, Wilisch-Neumann, A, Kirches, E, Riek-Burchardt, M, Angenstein, F, Reifenberger, G, Riemenschneider, M, Meese, E, Panayotova-Dimitrova, D, Gutmann, DH andMawrin, C. miRNA-145 is downregulated in atypical and anaplastic meningiomas and negatively regulates motility and proliferation of meningioma cells. Oncogene. 2012 Oct 29.

Knieke K, Lingel H, Chamaon K, Brunner-Weinzierl MC. Migration of Th1 lymphocytes is regulated by CD152 (CTLA-4)-mediated signaling via PI3 kinase-dependent Akt activation. PloS ONE 7:e313914.

König S, Probst-Kepper M, Reinl T, Jeron A, Huehn J, Schraven B, Jänsch L. First insight into the kinome of human regulatory T cells. PLoS One.;7(7):e40896.doi:10.1371/journal.pone.0040896. 2012 Jul 16.

Lipka DB, Wagner MC, Dziadosz M, Schnöder T, Heidel F, Schemionek M, Melo JV, Kindler T, Müller-Tidow C, Koschmieder S, Fischer T. Intracellular Retention of ABL Kinase Inhibitors Determines Commitment to Apoptosis in CML Cells. PLoS One.2012;7(7): e40853. Epub. 2012 Jul 16.

Mertens PR, Martin IV, Frye BC, Rauen T, Strauch S, Pabst M, Geier A. Rat Mrp2 gene expression is regulated by an interleukin-1beta-stimulated biphasic response with enhanced transcription and subcellular shuttling of YB-1. Eur J Cell Biol. 2012 Jun-Jul;91(6-7):533-41.

Mueller H, Herter JM,Rossaint J, Stadtmann A, Kliche S, Spieker T, Lowell CA, Zarbock A. Crucial role of SLP-76 and ADAP for neutrophil recruitment in mouse kidney ischemia-reperfusion injury. J Exp Med. 2012 Feb 13;209(2):407-21.

Navarro G, Hradsky J, Lluís C, Casadó V, McCormick PJ, Kreutz MR, Mikhaylova M. NCS-1 associates with adenosine A(2A) receptors and modulates receptor function. Front Mol Neurosci. 2012;5:53.

Pielot R, Smalla KH, Müller A, Landgraf P, Lehmann AC, Eisenschmidt E, Haus UU, Weissmantel R, Gundelfinger ED, Dieterich DC. SynProt: A Database for Proteins of Detergent-Resistant Synaptic Protein Preparations. Front Synaptic Neurosci. 2012;4:1.

Pierau, M, Na, SY, Simma, N, Lowinus, T, Marx, A, Schraven, B, Bommhardt, UH. Constitutive Akt1 signals attenuate B-cell receptor signaling and proliferation, but enhance B-cell migration and effector function. Eur J Immunol. 2012 Dec;42(12):3381-93.

Piotukh K, Freund C. A novel hSH3 domain scaffold engineered to bind folded domains in CD2BP2 and HIV capsid protein. PEDS pp.1-8,2012.

Poltz R, Naumann M. Dynamics of p53 and NF-kB regulation in response to DNA damage and identification of target proteins suitable for therapeutic intervention. BMC Syst Biol. 2012 Sep 15;6:125.

Raffetseder U, Liehn EA, Weber C, Mertens PR. Role of cold shock Y-box protein-1 in inflammation, atherosclerosis and organ transplant rejection. Eur J Cell Biol. 2012 Jun-Jul;91(6-7):567-75.

Schmeisser MJ, Ey E, Wegener S, Bockmann J, Stempel AV, Kuebler A, Janssen AL, Udvardi PT, Shiban E, Spilker C, Balschun D, Skryabin BV, Dieck St, Smalla KH, Montag D, Leblond CS, Faure P, Torquet N, Le Sourd AM, Toro R, Grabrucker AM, Shoichet SA, Schmitz D, Kreutz MR, Bourgeron T, Gundelfinger ED, Boeckers TM. Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2. Nature. 2012 Apr 29;486(7402):256-60.

Shalapour S, Deiser K, Kühl AA, Glauben R, Krug SM, Fischer A, Sercan O, Chappaz S, Bereswill S, Heimesaat MM, Loddenkemper C, Fromm M, Finke D, Hämmerling GJ, Arnold B, Siegmund B, Schüler T. Interleukin-7 links T lymphocyte and intestinal epithelial cell homeostasis. PLoS One. 2012;7(2):e31939

Stephanowitz H, Lange S, Lang D, Freund C, Krause E. An improved two-dimensional reversed phase-reversed phase LC-MS/MS approach for identification of peptide-protein interactions. J Proteome Res. 2012 Feb 3;11(2):1175-83.

Stielke S, Keilhoff G, Kirches E, Mertens PR, Neumann KH, Tsokos GC, Mawrin C. Adhesion molecule expression precedes brain damages of lupus-prone mice and correlates with kidney pathology. J Neuroimmunol. 2012 Nov 15;252(1-2):24-32.

Thaventhiran JE, A Hoffmann, L Magiera, M de la Roche, H Lingel, Brunner-Weinzierl MC, Fearon DT. Activation of the Hippo pathway by CTLA-4 regulates the expression of Blimp-1 in the CD8+ T cell. Proc Natl Acad Sci U S A 109:2223-2229.

Warnecke N, Poltorak M, Kowtharapu BS, Arndt B, Stone JC, Schraven B, Simeoni L. TCR-mediated Erk activation does not depend on Sos and Grb2 in peripheral human T cells. EMBO Rep. 2012 Apr;13(4):386-91.

Wienecke J, Hebel K, Hegel KJ, Pierau M, Brune T, Reinhold D, Pethe A, Brunner-Weinzierl MC. Pro-inflammatory effector Th cells transmigrate through anti-inflammatory environments into the murine fetus. Placenta. 2012 Jan;33(1):39-46. Epub 2011 Nov 16.

Witte A, Degen J, Baumgart K, Waldt N, Kuropka B, Freund C, Schraven B, Kliche S. Emerging Roles of ADAP, SKAP55, and SKAP-HOM for Integrin and NF-κB Signaling in T cells. Clinical and Cellular Immunology ISSN: 2155-9899.

Zenclussen AC, Olivieri DN, Dustin ML, Tadokoro CE. In vivo multiphoton microscopy technique to reveal the physiology of the mouse placenta. Am J Reprod Immunol. 2012 Sep;68(3):271-8.

Zenclussen ML, Jensen F, Rebelo S, El-Mousleh T, Casalis PA, Zenclussen AC. Heme Oxygenase-1 expression in the ovary dictates a proper oocyte ovulation, fertilization and corpora lutea maintenance. Am J Reprod Immunol. 2012 May;67(5):376-82.