A 29N - Functional role of neuronal ageing on neuron-T cell interaction during viral CNS infection

In project A29N, we will deliver insights into the molecular dynamics regulating the age-dependent interplay of the immune and nervous system. We will use new cultivation techniques mimicking neuronal ageing in vitro and cell type specific metabolic labeling in vivo to investigate CD8+ T cell/neuron interactions during systemic infection with neurotropic Langat virus.